Structure of PDB 2ql2 Chain A

Receptor sequence
>2ql2A (length=56) Species: 10090 (Mus musculus) [Search protein sequence]
RRMANNARERVRVRDINEAFRELGRMCQLHLKAQTKLLILQQAVQVILGL
EQQVRE
3D structure
PDB2ql2 Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R550 E551 R554 R8 E9 R12 PDBbind-CN: Kd=3.5nM
BS02 dna A R544 N548 E551 R552 N559 T580 K581 R2 N6 E9 R10 N17 T35 K36 PDBbind-CN: Kd=3.5nM
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:2ql2, PDBe:2ql2, PDBj:2ql2
PDBsum2ql2
PubMed18069799
UniProtP15806|TFE2_MOUSE Transcription factor E2-alpha (Gene Name=Tcf3)

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