Structure of PDB 2qki Chain A

Receptor sequence
>2qkiA (length=631) Species: 9606 (Homo sapiens) [Search protein sequence]
PMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEK
TVLTPATNHMGNVTFTIPANRGRNKFVTVQATFGTQVVEKVVLVSLQSGY
LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDS
LSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVL
PSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGE
QRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQRAEDLVGKSLYVSATVI
LHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDG
SPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQEL
SEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDR
AHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRL
VAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSQPVPGQQMTLK
IEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKD
YAGVFSDAGLTFTSSSGQQTAQRAELQCPQP
3D structure
PDB2qki Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G345 P347 N390 T391 L454 R456 M457 R459 E462 R486 G489 D491 G336 P338 N381 T382 L445 R447 M448 R450 E453 R477 G480 D482
Gene Ontology
Molecular Function
GO:0004866 endopeptidase inhibitor activity

View graph for
Molecular Function
External links
PDB RCSB:2qki, PDBe:2qki, PDBj:2qki
PDBsum2qki
PubMed17684013
UniProtP01024|CO3_HUMAN Complement C3 (Gene Name=C3)

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