Structure of PDB 2qjc Chain A

Receptor sequence
>2qjcA (length=222) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLV
NKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVE
TYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTL
TATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVY
GGRLSAAVFPGGCIISVPGWNG
3D structure
PDB2qjc Structural genomics of protein phosphatases.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.41: bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D26 H28 D55 D19 H21 D48
BS02 MN A D55 N81 H141 H204 D48 N74 H121 H177
Gene Ontology
Molecular Function
GO:0000298 endopolyphosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0006798 polyphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2qjc, PDBe:2qjc, PDBj:2qjc
PDBsum2qjc
PubMed18058037
UniProtQ57U41

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