Structure of PDB 2qic Chain A

Receptor sequence
>2qicA (length=51) Species: 9606 (Homo sapiens) [Search protein sequence]
EPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRG
E
3D structure
PDB2qic Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y212 S219 Y220 G221 E222 M223 I224 G225 E234 W235 F238 K246 P247 G249 Y4 S11 Y12 G13 E14 M15 I16 G17 E26 W27 F30 K38 P39 G41
BS02 ZN A C213 C215 H237 C240 C5 C7 H29 C32
BS03 ZN A C226 C231 C253 C256 C18 C23 C45 C48
External links
PDB RCSB:2qic, PDBe:2qic, PDBj:2qic
PDBsum2qic
PubMed18533182
UniProtQ9UK53|ING1_HUMAN Inhibitor of growth protein 1 (Gene Name=ING1)

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