Structure of PDB 2qic Chain A
Receptor sequence
>2qicA (length=51) Species:
9606
(Homo sapiens) [
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EPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRG
E
3D structure
PDB
2qic
Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
Chain
A
Resolution
2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
A
Y212 S219 Y220 G221 E222 M223 I224 G225 E234 W235 F238 K246 P247 G249
Y4 S11 Y12 G13 E14 M15 I16 G17 E26 W27 F30 K38 P39 G41
BS02
ZN
A
C213 C215 H237 C240
C5 C7 H29 C32
BS03
ZN
A
C226 C231 C253 C256
C18 C23 C45 C48
External links
PDB
RCSB:2qic
,
PDBe:2qic
,
PDBj:2qic
PDBsum
2qic
PubMed
18533182
UniProt
Q9UK53
|ING1_HUMAN Inhibitor of growth protein 1 (Gene Name=ING1)
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