Structure of PDB 2qgw Chain A

Receptor sequence
>2qgwA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB2qgw NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ChainA
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 L372 E542 M543 I54 L68 E230 M231
BS02 EES A M343 L346 T347 A350 E353 L387 H524 L525 M39 L42 T43 A46 E49 L83 H212 L213
External links
PDB RCSB:2qgw, PDBe:2qgw, PDBj:2qgw
PDBsum2qgw
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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