Structure of PDB 2qgt Chain A

Receptor sequence
>2qgtA (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB2qgt NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 N359 K362 L372 V376 D538 L539 E542 I54 N55 K58 L68 V72 D227 L228 E231
BS02 EED A L346 A350 E353 W383 F404 H524 L525 L42 A46 E49 W79 F100 H213 L214
External links
PDB RCSB:2qgt, PDBe:2qgt, PDBj:2qgt
PDBsum2qgt
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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