Structure of PDB 2qb8 Chain A

Receptor sequence
>2qb8A (length=393) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
RKTVPEFLAHLKSLPISKIASNDVLTICVGNESADMDSIASAITYSYCQY
IYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFF
IEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQK
HLDAEPRIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTS
NMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDI
KGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGGEADF
VNQCRRFQAERGLDVLVLLTSWRKAGDSHRELVILGDSNVVRELIERVSD
KLQLQLFGGNLDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE
3D structure
PDB2qb8 The crystal structure of the cytosolic exopolyphosphatase from Saccharomyces cerevisiae reveals the basis for substrate specificity.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.11: exopolyphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D41 D127 H148 D37 D123 H144
BS02 ATP A K268 S286 T380 R381 K264 S282 T376 R377
Gene Ontology
Molecular Function
GO:0004309 exopolyphosphatase activity
GO:0005524 ATP binding
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006798 polyphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qb8, PDBe:2qb8, PDBj:2qb8
PDBsum2qb8
PubMed17599355
UniProtP38698|PPX1_YEAST Polyphosphatase (Gene Name=PPX1)

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