Structure of PDB 2qb6 Chain A

Receptor sequence
>2qb6A (length=393) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
RKTVPEFLAHLKSLPISKIASNDVLTICVGNESADMDSIASAITYSYCQY
IYNEGTYSEEKKKGSFIVPIIDIPREDLSLRRDVMYVLEKLKIKEEELFF
IEDLKSLKQNVSQGTELNSYLVDNNDTPKNLKNYIDNVVGIIDHHFDLQK
HLDAEPRIVKVSGSCSSLVFNYWYEKLQGDREVVMNIAPLLMGAILIDTS
NMRRKVEESDKLAIERCQAVLSGAVNEVSAQGLEDSSEFYKEIKSRKNDI
KGFSVSDILKKDYKQFNFQGKGHKGLEIGLSSIVKRMSWLFNEHGGEADF
VNQCRRFQAERGLDVLVLLTSWRKAGDSHRELVILGDSNVVRELIERVSD
KLQLQLFGGNLDGGVAMFKQLNVEATRKQVVPYLEEAYSNLEE
3D structure
PDB2qb6 The crystal structure of the cytosolic exopolyphosphatase from Saccharomyces cerevisiae reveals the basis for substrate specificity.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.11: exopolyphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D41 D127 H148 D37 D123 H144
Gene Ontology
Molecular Function
GO:0004309 exopolyphosphatase activity
GO:0005524 ATP binding
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006798 polyphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2qb6, PDBe:2qb6, PDBj:2qb6
PDBsum2qb6
PubMed17599355
UniProtP38698|PPX1_YEAST Polyphosphatase (Gene Name=PPX1)

[Back to BioLiP]