Structure of PDB 2q8q Chain A

Receptor sequence
>2q8qA (length=258) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence]
GEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPN
VEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQ
LGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLV
ATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGM
PEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMT
QLYDLFYK
3D structure
PDB2q8q Heme Coordination by Staphylococcus aureus IsdE.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A T40 V41 A42 S60 Y61 P77 M78 I99 V175 P176 H229 G230 I270 T9 V10 A11 S29 Y30 P46 M47 I68 V144 P145 H198 G199 I239
Gene Ontology
Molecular Function
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0015886 heme transport
GO:0071281 cellular response to iron ion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2q8q, PDBe:2q8q, PDBj:2q8q
PDBsum2q8q
PubMed17666394
UniProtQ7A652|ISDE_STAAN High-affinity heme uptake system protein IsdE (Gene Name=isdE)

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