Structure of PDB 2q7k Chain A

Receptor sequence
>2q7kA (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIASCSRRFYQLTKLLDSVQPIARELYQFT
FDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB2q7k Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V716 K720 Q733 M734 I737 Q738 E893 M894 E897 V46 K50 Q63 M64 I67 Q68 E216 M217 E220
BS02 TES A L701 L704 N705 Q711 M745 F764 M780 T877 M895 L31 L34 N35 Q41 M75 F94 M110 T200 M218 BindingDB: IC50=2.7nM,Ki=3.2nM,EC50=1.1nM
External links
PDB RCSB:2q7k, PDBe:2q7k, PDBj:2q7k
PDBsum2q7k
PubMed17591767
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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