Structure of PDB 2q6j Chain A

Receptor sequence
>2q6jA (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB2q6j Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 V376 L539 E542 M543 I53 K57 V71 L232 E235 M236
BS02 A48 A M343 L346 T347 L384 F404 M421 I424 G521 H524 L525 L540 M38 L41 T42 L79 F99 M116 I119 G214 H217 L218 L233
External links
PDB RCSB:2q6j, PDBe:2q6j, PDBj:2q6j
PDBsum2q6j
PubMed17584613
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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