Structure of PDB 2q4v Chain A

Receptor sequence
>2q4vA (length=156) Species: 9606 (Homo sapiens) [Search protein sequence]
SVRIREAKEGDCGDILRLIRELAEFEKLKISEEALRADGFGDNPFYHCLV
AEILGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYRGQGIGSKIIKKV
AEVALDKGCSQFRLAVLDWNQRAMDLYKALGAQDLTEAEGWHFFCFQGEA
TRKLAG
3D structure
PDB2q4v Ensemble refinement of protein crystal structures: validation and application.
ChainA
Resolution1.842 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO A L24 F27 E92 I94 Y95 V96 R101 G102 G104 G106 S107 L127 A128 N133 R135 L139 Y140 L22 F25 E79 I81 Y82 V83 R88 G89 G91 G93 S94 L114 A115 N120 R122 L126 Y127
Gene Ontology
Molecular Function
GO:0004145 diamine N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042802 identical protein binding
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0032918 spermidine acetylation
GO:0032919 spermine acetylation
GO:0032920 putrescine acetylation
GO:0046204 nor-spermidine metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2q4v, PDBe:2q4v, PDBj:2q4v
PDBsum2q4v
PubMed17850744
UniProtQ96F10|SAT2_HUMAN Thialysine N-epsilon-acetyltransferase (Gene Name=SAT2)

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