Structure of PDB 2q2r Chain A

Receptor sequence
>2q2rA (length=370) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
APAGSHMNIKELSLHELCEELKTPAWNAPLTFVGDVGGTSARMGFVREGK
NDSVHACVTRYSMKRKDITEIIEFFNEIIELMPASVMKRVKAGVINVPGP
VTGGAVGGPFNNLKGIARLSDYPKALFPPGHSAILNDLEAGGFGVLAVSD
AHVFSEYFGVMWEGTQWRTCEQEPAGSVIGRGRCLVLAPGTGLGSSLIYY
NPQHIVVPLELGSQTLPMRKDIDYIQTLHAELKLFPNYENMVSGAGLEFH
YRQVVRGSRPPCSAGEIAKLASEGDANACKAMKKYHEYLMRVGSEASMAL
LPLTIVLVGDNIVNNAFFYRNPQNLKEMHHEALNHEMERFGFQSRVSYLR
QKKLLNLNLMGCYRCGLDLS
3D structure
PDB2q2r The Crystal Structure of Trypanosoma cruzi Glucokinase Reveals Features Determining Oligomerization and Anomer Specificity of Hexose-phosphorylating Enzymes.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.2: glucokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A G93 D131 L187 G188 E207 E236 G99 D137 L193 G194 E210 E239
BS02 ADP A G184 T185 A261 A265 N308 N312 G190 T191 A264 A268 N311 N315
Gene Ontology
Molecular Function
GO:0004340 glucokinase activity
GO:0005524 ATP binding
GO:0005536 D-glucose binding
Biological Process
GO:0006096 glycolytic process
GO:0051156 glucose 6-phosphate metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2q2r, PDBe:2q2r, PDBj:2q2r
PDBsum2q2r
PubMed17761195
UniProtQ4E4E1

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