Structure of PDB 2pz0 Chain A

Receptor sequence
>2pz0A (length=239) Species: 273068 (Caldanaerobacter subterraneus subsp. tengcongensis MB4) [Search protein sequence]
KTLVIAHRGDSKNVPENTIAAFKRAMELGADGIELDVQLTKDGHLVVIHD
ETVDRTTNGEGFVKDFTLEEIKKLDAGIKFGEKFAGERIPTLYEVFELIG
DKDFLVNIEIKSGIVLYPGIEEKLIKAIKEYNFEERVIISSFNHYSLRDV
KKMAPHLKIGLLYQCGLVEPWHMALRMEAYSLHPFYFNIIPELVEGCKKN
GVKLFPWTVDRKEDMERMIKAGVDGIITDDPETLINLVR
3D structure
PDB2pz0 Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism.
ChainA
Resolution1.91 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H17 R18 E44 D46 H59 E119 K121 D239
Catalytic site (residue number reindexed from 1) H7 R8 E34 D36 H49 E109 K111 D229
Enzyme Commision number 3.1.4.46: glycerophosphodiester phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E44 D46 E119 E34 D36 E109
BS02 GOL A H17 E44 F152 L172 W217 H7 E34 F142 L162 W207
Gene Ontology
Molecular Function
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2pz0, PDBe:2pz0, PDBj:2pz0
PDBsum2pz0
PubMed18214974
UniProtQ8RB32|GDPD_CALS4 Glycerophosphodiester phosphodiesterase (Gene Name=UgpQ)

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