Structure of PDB 2pxh Chain A

Receptor sequence
>2pxhA (length=306) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
DEFEMIKRNTSEIISEEELREVLKKDEKSAGIGFEPSGKIHLGHYLQIKK
MIDLQNAGFDIIIYLADLAAYLNQKGELDEIRKIGDYNKKVFEAMGLKAK
YVYGSEFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIY
PIMEVNGWHYSGVDVAVGGMEQRKIHMLARELLPKKVVCIHNPVLTGLDG
EGKMSSSKGNFIAVDDSPEEIRAKIKKAYCPAGVVEGNPIMEIAKYFLEY
PLTIKRPEKFGGDLTVNSYEELESLFKNKELHPMDLKNAVAEELIKILEP
IRKRLL
3D structure
PDB2pxh A genetically encoded bidentate, metal-binding amino acid.
ChainA
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.1: tyrosine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BP5 A G34 Y65 Y151 E155 G158 W159 Q173 G33 Y64 Y150 E154 G157 W158 Q172
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2pxh, PDBe:2pxh, PDBj:2pxh
PDBsum2pxh
PubMed17893898
UniProtQ57834|SYY_METJA Tyrosine--tRNA ligase (Gene Name=tyrS)

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