Structure of PDB 2pvi Chain A

Receptor sequence
>2pviA (length=156) Species: 585 (Proteus vulgaris) [Search protein sequence]
SHPDLNKLLELWPHIQEYQDLALKHGINDIFQDNGGKLLQVLLITGLTVL
PGRAGNDAVDNAGQEYELKSINIDLTKGFSTHHHMNPVIIAKARQVPWIF
AIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVME
HGTKIY
3D structure
PDB2pvi How is modification of the DNA substrate recognized by the PvuII restriction endonuclease?
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q33 Y123 K130 N140 P145 Q32 Y122 K129 N139 P144
BS02 dna A D34 N35 A55 N57 S71 L76 S81 T82 H83 H84 K93 N141 K143 D33 N34 A54 N56 S70 L75 S80 T81 H82 H83 K92 N140 K142
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:2pvi, PDBe:2pvi, PDBj:2pvi
PDBsum2pvi
PubMed9628337
UniProtP23657|T2P2_PROHU Type II restriction enzyme PvuII (Gene Name=pvuIIR)

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