Structure of PDB 2prt Chain A

Receptor sequence

>2prtA (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]

RPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQL
KRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQK
KFARSDELVRHHNMH

3D structure

PDB

2prt Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA

Chain

Resolution

3.15 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	R366 R372 H373 R376 R390 F392 S393 R394 H397 H401 R424 E427 R430	R46 R52 H53 R56 R70 F72 S73 R74 H77 H81 R104 E107 R110
BS02	dna	A	A326 Y327 P328 R366 S367 D368 D396 K399 S425	A6 Y7 P8 R46 S47 D48 D76 K79 S105
BS03	ZN	A	C325 C330 H343 H347	C5 C10 H23 H27
BS04	ZN	A	C355 C360 H373 H377	C35 C40 H53 H57
BS05	ZN	A	C385 C388 H401 H405	C65 C68 H81 H85
BS06	ZN	A	C413 C418 H431 H435	C93 C98 H111 H115

External links

PDB	RCSB:2prt, PDBe:2prt, PDBj:2prt
PDBsum	2prt
PubMed	17716689
UniProt	P19544\|WT1_HUMAN Wilms tumor protein (Gene Name=WT1)