Structure of PDB 2pnz Chain A

Receptor sequence
>2pnzA (length=236) Species: 29292 (Pyrococcus abyssi) [Search protein sequence]
KLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYG
PRELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGA
LEPALILEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDL
VAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLT
KDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQE
3D structure
PDB2pnz Insights into the mechanism of progressive RNA degradation by the archaeal exosome.
ChainA
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A M81 V86 R97 A134 G135 T136 R137 D180 M73 V78 R89 A126 G127 T128 R129 D172
BS02 5GP A R89 K91 R81 K83
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0004527 exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
Biological Process
GO:0006401 RNA catabolic process
GO:0016075 rRNA catabolic process
Cellular Component
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2pnz, PDBe:2pnz, PDBj:2pnz
PDBsum2pnz
PubMed18353775
UniProtQ9V119|RRP41_PYRAB Exosome complex component Rrp41 (Gene Name=rrp41)

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