Structure of PDB 2pny Chain A

Receptor sequence
>2pnyA (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
LVPRGSMSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNEN
IEKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPA
ELEEKDAIGVRRAAQRRLQAELGIPGEQISPEDIVFMTIYHHKAKSDRIW
GEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELWELLEREARGEVKVT
PWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV
3D structure
PDB2pny Structure of the human Isopentenyl-diphosphate Delta-isomerase 2.
ChainA
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.3.2: isopentenyl-diphosphate Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A S86 E115 S92 E121
BS02 MN A H40 H51 H88 E146 E148 H46 H57 H94 E152 E154
BS03 POP A R16 K36 R70 K74 S86 S87 R111 R22 K42 R76 K80 S92 S93 R117
Gene Ontology
Molecular Function
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006695 cholesterol biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0009240 isopentenyl diphosphate biosynthetic process
GO:0046490 isopentenyl diphosphate metabolic process
GO:0050992 dimethylallyl diphosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2pny, PDBe:2pny, PDBj:2pny
PDBsum2pny
PubMed
UniProtQ9BXS1|IDI2_HUMAN Isopentenyl-diphosphate delta-isomerase 2 (Gene Name=IDI2)

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