Structure of PDB 2pk4 Chain A

Receptor sequence
>2pk4A (length=80) Species: 9606 (Homo sapiens) [Search protein sequence]
QDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMN
YCRNPDADKGPWCFTTDPSVRWEYCNLKKC
3D structure
PDB2pk4 The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ACA A K35 D55 D57 W62 F64 R71 W72 K37 D56 D58 W62 F64 R71 W72 BindingDB: Ki=53000000nM,Kd=9000nM,IC50=105000nM
External links
PDB RCSB:2pk4, PDBe:2pk4, PDBj:2pk4
PDBsum2pk4
PubMed1657149
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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