Structure of PDB 2pf2 Chain A

Receptor sequence
>2pf2A (length=145) Species: 9913 (Bos taurus) [Search protein sequence]
ANKGFLEEVRKGNLERECLEEPCSREEAFEALESLSATDAFWAKYTACES
ARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEI
NSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCG
3D structure
PDB2pf2 The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A E26 E30 G145 E26 E30 G145
BS02 CA A E8 E27 E30 E8 E27 E30
BS03 CA A E8 E17 E27 E30 E8 E17 E27 E30
BS04 CA A A1 N2 E7 E8 E17 E27 A1 N2 E7 E8 E17 E27
BS05 CA A A1 E7 E17 E21 A1 E7 E17 E21
BS06 CA A E20 E21 E20 E21
BS07 CA A E15 E20 E15 E20
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:2pf2, PDBe:2pf2, PDBj:2pf2
PDBsum2pf2
PubMed1547238
UniProtP00735|THRB_BOVIN Prothrombin (Gene Name=F2)

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