Structure of PDB 2peg Chain A

Receptor sequence

>2pegA (length=142) Species: 40690 (Trematomus bernacchii)

SLSDKDKAAVRALWSKIGKSADAIGNDALSRMIVVYPQTKTYFSHWPDVT
PGSPHIKAHGKKVMGGIALAVSKIDDLKTGLMELSEQHAYKLRVDPANFK
ILNHCILVVISTMFPKEFTPEAHVSLDKFLSGVALALAERYR

3D structure

• PDB: 2peg Structural characterization of ferric hemoglobins from three antarctic fish species of the suborder notothenioidei.
• Chain: A
• Resolution: 1.48 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	Y42 F43 H45 H59 K62 L84 Q87 H88 L92 V94 N98 F99 L102 L137	Y42 F43 H45 H59 K62 L84 Q87 H88 L92 V94 N98 F99 L102 L137

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0005506 iron ion binding
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:2peg, PDBe:2peg, PDBj:2peg
• PDBsum: 2peg
• PubMed: 17545238
• UniProt: P80043|HBA_TREBE Hemoglobin subunit alpha (Gene Name=hba)