Structure of PDB 2pb1 Chain A

Receptor sequence
>2pb1A (length=394) Species: 5476 (Candida albicans) [Search protein sequence]
AWDYDNNVIRGVNLGGWFVLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQ
TLGKEAALRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDND
PYVQGQVQYLEKALGWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQ
NGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPVLNMDKLKQF
FLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLTVAEGQWNVVVDHHHYQ
VFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDCAKWLNG
VNRGARYEGAYDNAPYIGSCQPLLDISQWSDEHKTDTRRYIEAQLDAFEY
TGGWVFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH
3D structure
PDB2pb1 The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E192 E292
Catalytic site (residue number reindexed from 1) E186 E286
Enzyme Commision number 2.4.1.-
3.2.1.58: glucan 1,3-beta-glucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G2F A E27 Y29 H135 N146 Y255 E292 W363 E21 Y23 H129 N140 Y249 E286 W357
BS02 NFG A E192 F229 Y255 E186 F223 Y249
Gene Ontology
Molecular Function
GO:0004338 glucan exo-1,3-beta-glucosidase activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016740 transferase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0006696 ergosterol biosynthetic process
GO:0007155 cell adhesion
GO:0009251 glucan catabolic process
GO:0031505 fungal-type cell wall organization
GO:0031589 cell-substrate adhesion
GO:0044011 single-species biofilm formation on inanimate substrate
GO:0044042 glucan metabolic process
GO:0044407 single-species biofilm formation in or on host organism
GO:0071555 cell wall organization
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface
GO:1903561 extracellular vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2pb1, PDBe:2pb1, PDBj:2pb1
PDBsum2pb1
PubMed
UniProtP29717|EXG1_CANAL Glucan 1,3-beta-glucosidase (Gene Name=XOG1)

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