Structure of PDB 2p9i Chain A

Receptor sequence
>2p9iA (length=393) Species: 9913 (Bos taurus) [Search protein sequence]
GRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKEKGVDDLDFFIGDE
AIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEP
PLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTG
TVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGI
PPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKK
EFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPL
YKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSKPKPIDVQVIT
HHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNP
3D structure
PDB2p9i Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
ChainA
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A T14 G15 Y16 K18 G171 D172 K225 K228 E229 G324 M327 F328 R374 T12 G13 Y14 K16 G156 D157 K210 K213 E214 G309 M312 F313 R355
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0010592 positive regulation of lamellipodium assembly
GO:0030030 cell projection organization
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060271 cilium assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0035861 site of double-strand break
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2p9i, PDBe:2p9i, PDBj:2p9i
PDBsum2p9i
PubMed17499050
UniProtP61157|ARP3_BOVIN Actin-related protein 3 (Gene Name=ACTR3)

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