Structure of PDB 2p8e Chain A

Receptor sequence
>2p8eA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
FLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDW
SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRSVENVKNGIRTGFLKID
EYMRNFSDLRDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQ
DHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTE
QLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDD
LENVCNWVVDTCLHKGSRDNMSIVLVCF
3D structure
PDB2p8e Structural genomics of protein phosphatases.
ChainA
Resolution1.816 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D60 C242 D243 D286 D57 C225 D226 D269
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2p8e, PDBe:2p8e, PDBj:2p8e
PDBsum2p8e
PubMed18058037
UniProtO75688|PPM1B_HUMAN Protein phosphatase 1B (Gene Name=PPM1B)

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