Structure of PDB 2p7a Chain A

Receptor sequence
>2p7aA (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]
YNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWA
KHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMD
EDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQ
HFYNIKLEGKVPMHKLFLEMLEA
3D structure
PDB2p7a Structural determination of estrogen-related receptor gamma in the presence of phenol derivative compounds.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 43M A E275 L309 V313 Y326 F435 E42 L76 V80 Y93 F202 MOAD: Kd=0.788uM
PDBbind-CN: -logKd/Ki=6.10,Kd=0.788uM
External links
PDB RCSB:2p7a, PDBe:2p7a, PDBj:2p7a
PDBsum2p7a
PubMed17964775
UniProtP62508|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)

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