Structure of PDB 2p39 Chain A

Receptor sequence
>2p39A (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
SPLLGSSWGGLIHLYTATARNSYHLQIHKNGHVDGAPHQTIYSALMIRSE
DAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTLENGYDVYH
SPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFN
3D structure
PDB2p39 Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GU4 A R48 N49 R20 N21
BS02 YYJ A A47 R48 N49 G139 A141 P153 Y154 A19 R20 N21 G111 A113 P125 Y126
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:2p39, PDBe:2p39, PDBj:2p39
PDBsum2p39
PubMed17339340
UniProtQ9GZV9|FGF23_HUMAN Fibroblast growth factor 23 (Gene Name=FGF23)

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