Structure of PDB 2p1h Chain A

Receptor sequence
>2p1hA (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPT
QQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIP
3D structure
PDB2p1h Rapid Folding and Unfolding of Apaf-1 CARD.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D29 E42 D29 E42
BS02 ZN A H30 D34 H30 D34
BS03 ZN A C10 D91 C10 D91
BS04 ZN A D66 D68 D66 D68
Gene Ontology
Molecular Function
GO:0002020 protease binding
GO:0070513 death domain binding
Biological Process
GO:0042981 regulation of apoptotic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2p1h, PDBe:2p1h, PDBj:2p1h
PDBsum2p1h
PubMed17408690
UniProtO14727|APAF_HUMAN Apoptotic protease-activating factor 1 (Gene Name=APAF1)

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