Structure of PDB 2owq Chain A

Receptor sequence
>2owqA (length=216) Species: 696871 (Vaccinia virus Western Reserve) [Search protein sequence]
SHMNSVTVSHAPYTITYHNDWEPVMSQLVEFYNEVASWLLRDETSPIPDK
FFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISR
LTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHI
TKHVSVLYCLGKTDFSNIRAKLEVTTIVGYHPAARDFEKDRSFEIINVLL
ELDNKAPINWAQGFIY
3D structure
PDB2owq Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GOL A K160 T161 H181 K162 T163 H181
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004844 uracil DNA N-glycosylase activity
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2owq, PDBe:2owq, PDBj:2owq
PDBsum2owq
PubMed17605817
UniProtP04303|UNG_VACCW Uracil-DNA glycosylase (Gene Name=OPG116)

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