Structure of PDB 2ovm Chain A

Receptor sequence
>2ovmA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
QLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVK
WSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPD
LILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIP
LEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLH
DLVKQLHLYCLNTFIQSRAMSEVIAAQLPKILAGMVKPLLFHK
3D structure
PDB2ovm A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L726 V730 K734 R740 I744 I748 I751 Q752 W755 L45 V49 K53 R59 I63 I67 I70 Q71 W74
BS02 AS0 A L718 N719 G722 E723 Q725 W755 M759 F794 L797 C891 L37 N38 G41 E42 Q44 W74 M78 F113 L116 C210
External links
PDB RCSB:2ovm, PDBe:2ovm, PDBj:2ovm
PDBsum2ovm
PubMed17356170
UniProtP06401|PRGR_HUMAN Progesterone receptor (Gene Name=PGR)

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