Structure of PDB 2os1 Chain A

Receptor sequence
>2os1A (length=179) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
MITMKDIIREGNPTLRAVAEEVPVPITEEDRQLGEDMLTFLKNSQDPVKA
EELQLRGGVGLAAPQLDISKRIIAVHVPSLSTVMYNPKILSHSVQDVCLG
EGEGCLSVDRDVPGYVVRHNKITVSYFDMAGEKHKVRLKNYEAIVVQHEI
DHINGIMFYDHINKENPFALKEGVLVIEL
3D structure
PDB2os1 Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G60 Q65 C114 L115 H157 E158 H161
Catalytic site (residue number reindexed from 1) G60 Q65 C105 L106 H148 E149 H152
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BB2 A G58 V59 G60 Q65 L108 E110 G111 G113 C114 L115 Y150 I153 H157 E158 H161 L188 G58 V59 G60 Q65 L99 E101 G102 G104 C105 L106 Y141 I144 H148 E149 H152 L179
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:2os1, PDBe:2os1, PDBj:2os1
PDBsum2os1
PubMed
UniProtQ82ZJ0|DEF_ENTFA Peptide deformylase (Gene Name=def)

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