Structure of PDB 2oqj Chain A

Receptor sequence

>2oqjA (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]

VVMTQSPSTLSASVGDTITITCRASQSIETWLAWYQQKPGKAPKLLIYKA
STLKTGVPSRFSGSGSGTEFTLTISGLQFDDFATYHCQHYAGYSATFGQG
TRVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVD
NALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGL
SSPVTKSFNRG

3D structure

PDB

2oqj A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.

Chain

Resolution

2.8 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	W32 H90 A92 G93 Y94 S95	W31 H89 A91 G92 Y93 S94

External links

PDB	RCSB:2oqj, PDBe:2oqj, PDBj:2oqj
PDBsum	2oqj
PubMed	18198210

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