Structure of PDB 2olo Chain A

Receptor sequence

>2oloA (length=393) Species: 1932 (Streptomyces tendae) [Search protein sequence]

TESYDVVVVGGGPVGLATAWQVAERGHRVLVLERHTFFNENGGTSGAERH
WRLQYTQEDLFRLTLETLPLWRALESRCERRLIHEIGSLWFGDTDVVTNE
GQISGTAAMMDKLSVRYEWLKATDIERRFGFRGLPRDYEGFLQPDGGTID
VRGTLAALFTLAQAAGATLRAGETVTELVPDADGVSVTTDRGTYRAGKVV
LACGPYTNDLLEPLGARLAYSVYEMAIAAYRQATPVTEAPFWFAFQQPTP
QDTNLFYGFGHNPWAPGEFVRCGPDFEVDPLDHPSAATGVADRRQMDRLS
GWLRDHLPTVDPDPVRTSTCLAVLPTDPERQFFLGTARDLMTHGEKLVVY
GAGWAFKFVPLFGRICADLAVEDSTAYDISRLAPQSALLEHHH

3D structure

PDB

2olo NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: structures of closed and open forms at 1.15 and 1.90 A resolution

Chain

Resolution

1.9 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	S46 E49 R50 R53 E101 Y258 R272 D276 R305 C321 W355 K358
Catalytic site (residue number reindexed from 1)	S45 E48 R49 R52 E100 Y257 R271 D275 R304 C320 W354 K357
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G11 G13 P14 V15 L33 E34 R35 G43 G44 T45 R50 H51 V176 C204 G205 Y207 C321 L322 Y351 W355 A356 F357 K358	G10 G12 P13 V14 L32 E33 R34 G42 G43 T44 R49 H50 V175 C203 G204 Y206 C320 L321 Y350 W354 A355 F356 K357
BS02	6PC	A	R53 E101 F242 Y258 W355	R52 E100 F241 Y257 W354

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0008115	sarcosine oxidase activity
GO:0016491	oxidoreductase activity
GO:0050660	flavin adenine dinucleotide binding

View graph for
Molecular Function

External links

PDB	RCSB:2olo, PDBe:2olo, PDBj:2olo
PDBsum	2olo
PubMed	17697998
UniProt	Q9X9P9

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