Structure of PDB 2oke Chain A

Receptor sequence
>2okeA (length=123) Species: 10245 (Vaccinia virus) [Search protein sequence]
PVRFVKETNRAKSPTRQSPGAAGYDLYSAYDYTIPPGERQLIKTDISMSM
PKFCYGRIAPRSGLSLKGIDIGGGVIDEDYRGNIGVILINNGKCTFNVNT
GDRIAQLIYQRIYYPELEEVQSL
3D structure
PDB2oke Structures of vaccinia virus dUTPase and its nucleotide complexes.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A30 R69 G71 I77 D85
Catalytic site (residue number reindexed from 1) A22 R61 G63 I69 D77
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP A G82 V83 I84 D85 Y88 G93 G74 V75 I76 D77 Y80 G85
BS02 DUP A R69 S70 G71 R61 S62 G63
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2oke, PDBe:2oke, PDBj:2oke
PDBsum2oke
PubMed17452782
UniProtP17374|DUT_VACCW Deoxyuridine 5'-triphosphate nucleotidohydrolase (Gene Name=OPG046)

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