Structure of PDB 2okc Chain A

Receptor sequence
>2okcA (length=424) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
QSLTKKVWNLATTLAGQGIGFTDYITQLTYLLFLKMDAENVEMFGEESAI
PTGYQWADLIAFDGLDLVKQYEETLKLLSELDNLIGTIYTKAQNKIDKPV
YLKKVITMIDEEQWLIMDGDVKGAIYESILEKNGQDKKSGAGQYFTPRPL
IQAMVDCINPQMGETVCDPACGTGGFLLTAYDYMKGQSSKEKRDFLRDKA
LHGVDNTPLVVTLASMNLYLHGIGTDRSPIVCEDSLEKEPSTLVDVILAN
PPFGTRPAGSVDINRPDFYVETKNNQLNFLQHMMLMLKTGGRAAVVLPDN
VLFEAGAGETIRKRLLQDFNLHTILRLPTGIFYAQGVKANVLFFSKGQPT
KEIWFYDYRTDIKHTLATNKLERHHLDDFVSCYNNRVEIYDAENNPQGRW
RKYPVDEIIARDKTSLDITWIKPG
3D structure
PDB2okc Crystal structure of Type I restriction enzyme StySJI M protein (NP_813429.1) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A Q151 Y152 F153 T154 R156 A178 C179 G180 T181 G183 F184 D214 N215 D243 N259 P261 F288 Q143 Y144 F145 T146 R148 A170 C171 G172 T173 G175 F176 D205 N206 D234 N250 P252 F279
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2okc, PDBe:2okc, PDBj:2okc
PDBsum2okc
PubMed
UniProtQ89Z59|T1M_BACTN Type I restriction enzyme BthVORF4518P methylase subunit (Gene Name=hsdM)

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