Structure of PDB 2odd Chain A
Receptor sequence
>2oddA (length=50) Species:
9606
(Homo sapiens) [
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DSSESCWNCGRKASETCSGCNTARYCGSFCQHKDWEKHHHICGQTLQAQQ
3D structure
PDB
2odd
Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Chain
A
Resolution
N/A
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
A
S671 E672 T673 C674 S675 G676 Q688 H689 W692 E693
S14 E15 T16 C17 S18 G19 Q31 H32 W35 E36
BS02
ZN
A
C663 C666 C683 C687
C6 C9 C26 C30
BS03
ZN
A
C674 C677 H695 C699
C17 C20 H38 C42
Gene Ontology
Molecular Function
GO:0003714
transcription corepressor activity
Biological Process
GO:0045892
negative regulation of DNA-templated transcription
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Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:2odd
,
PDBe:2odd
,
PDBj:2odd
PDBsum
2odd
PubMed
17560331
UniProt
Q06455
|MTG8_HUMAN Protein CBFA2T1 (Gene Name=RUNX1T1)
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