Structure of PDB 2o99 Chain A

Receptor sequence
>2o99A (length=178) Species: 562 (Escherichia coli) [Search protein sequence]
GHMSRNLLAIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLM
RMSAPIGGKLPMHASGAGKAFLAQLSEEQVTKKGLHAYTHATLVSPVHLK
EDLAQTRKRGYSFDDEEHALGLRCLAACIFDEHREPFAAISISGPISRIT
DDRVTEFGAMVIKAAKEVTLAYGGMRGS
3D structure
PDB2o99 Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOA A L60 S65 G66 D118 C128 S145 S147 L60 S65 G66 D114 C124 S141 S143 Manual survey: Kd=0.9+-2uM (17426033)
External links
PDB RCSB:2o99, PDBe:2o99, PDBj:2o99
PDBsum2o99
PubMed17426033
UniProtP16528|ICLR_ECOLI Transcriptional repressor IclR (Gene Name=iclR)

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