Structure of PDB 2o72 Chain A

Receptor sequence
>2o72A (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
DWVIPPISSPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGV
FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTD
QNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI
LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEG
LSTTATAVITVTD
3D structure
PDB2o72 The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N102 N104 D134 D136 N143 D195 N102 N104 D134 D136 N143 D195
BS02 CA A E11 E69 D100 Q101 D103 D136 E11 E69 D100 Q101 D103 D136
BS03 CA A E11 D67 E69 D103 E11 D67 E69 D103
BS04 CA A E119 D180 E119 D180
BS05 CA A E119 E182 D213 E119 E182 D213
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o72, PDBe:2o72, PDBj:2o72
PDBsum2o72
PubMed17850815
UniProtP12830|CADH1_HUMAN Cadherin-1 (Gene Name=CDH1)

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