Structure of PDB 2o2n Chain A

Receptor sequence
>2o2nA (length=145) Species: 9606 (Homo sapiens) [Search protein sequence]
SQSNRELVVDFLSYKLSQKGYSAGGGGGGGGMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
3D structure
PDB2o2n Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LIW A E100 F101 Y105 A108 L112 L134 W141 G142 R143 Y199 E45 F46 Y50 A53 L57 L79 W86 G87 R88 Y144
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2o2n, PDBe:2o2n, PDBj:2o2n
PDBsum2o2n
PubMed17256834
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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