Structure of PDB 2o1y Chain A

Receptor sequence
>2o1yA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
MSMAMSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEAV
KQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVN
WGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENG
GWDTFVELYGNNAAAESRKGQERLEHHHHHH
3D structure
PDB2o1y Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 43B A E100 F101 R104 Y105 A108 L112 Q115 V130 E133 L134 N140 G142 R143 V145 A146 Y199 E60 F61 R64 Y65 A68 L72 Q75 V90 E93 L94 N100 G102 R103 V105 A106 Y159
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2o1y, PDBe:2o1y, PDBj:2o1y
PDBsum2o1y
PubMed17256834
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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