Structure of PDB 2o0r Chain A

Receptor sequence
>2o0rA (length=385) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ATVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAI
AGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAA
AVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDAD
ALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEV
YEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAEL
IAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAA
GLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSA
FCDPADVWNHLVRFTFCKRDDTLDEAIRRLSVLAE
3D structure
PDB2o0r The Three-dimensional Structure of N-Succinyldiaminopimelate Aminotransferase from Mycobacterium tuberculosis
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y119 D198 V200 K232
Catalytic site (residue number reindexed from 1) Y119 D198 V200 K232
Enzyme Commision number 2.6.1.17: succinyldiaminopimelate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL A F14 D120 F14 D120
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008483 transaminase activity
GO:0009016 succinyldiaminopimelate transaminase activity
GO:0016212 kynurenine-oxoglutarate transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
Cellular Component
GO:0005737 cytoplasm
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o0r, PDBe:2o0r, PDBj:2o0r
PDBsum2o0r
PubMed17292400
UniProtP9WPZ5|DAPC_MYCTU Probable N-succinyldiaminopimelate aminotransferase DapC (Gene Name=dapC)

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