Structure of PDB 2o03 Chain A

Receptor sequence
>2o03A (length=129) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
ASAAGVRSTRQRAAISTLLETLDDFRSAQELHDELRRRGENIGLTTVYRT
LQSMASSGLVDTLHTDTGESVYRRCSEHHHHHLVCRSCGSTIEVGDHEVE
AWAAEVATKHGFSDVSHTIEIFGTCSDCR
3D structure
PDB2o03 Crystal structure and function of the zinc uptake regulator FurB from Mycobacterium tuberculosis.
ChainA
Resolution2.699 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D62 H81 H83 D61 H80 H82
BS02 ZN A C86 C89 C126 C129 C85 C88 C125 C128
BS03 ZN A H80 H82 E101 H118 H79 H81 E100 H117
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0010043 response to zinc ion
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:1900376 regulation of secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o03, PDBe:2o03, PDBj:2o03
PDBsum2o03
PubMed17213192
UniProtP9WN85|ZUR_MYCTU Zinc uptake regulation protein (Gene Name=zur)

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