Structure of PDB 2nxe Chain A

Receptor sequence
>2nxeA (length=254) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MWVYRLKGTLEALDPILPGLFDGGARGLWEREGEVWAFFPAPVDLPYEGV
WEEVGDEDWLEAWRRDLKPALAPPFVVLAPWHTWEGAEIPLVIEPGMAFG
TGHHETTRLALKALARHLRPGDKVLDLGTGSGVLAIAAEKLGGKALGVDI
DPMVLPQAEANAKRNGVRPRFLEGSLEAALPFGPFDLLVANLYAELHAAL
APRYREALVPGGRALLTGILKDRAPLVREAMAGAGFRPLEEAAEGEWVLL
AYGR
3D structure
PDB2nxe Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A F99 T107 G128 L134 D149 I150 S175 N191 L192 F99 T107 G128 L134 D149 I150 S175 N191 L192 MOAD: Kd=5.5uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006479 protein methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nxe, PDBe:2nxe, PDBj:2nxe
PDBsum2nxe
PubMed17215866
UniProtQ84BQ9|PRMA_THET8 Ribosomal protein L11 methyltransferase (Gene Name=prmA)

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