Structure of PDB 2nw4 Chain A

Receptor sequence
>2nw4A (length=248) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIA
RELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB2nw4 Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8NH A L701 L704 N705 L707 G708 M745 M749 F764 M780 T877 L31 L34 N35 L37 G38 M75 M79 F94 M110 T207 PDBbind-CN: -logKd/Ki=8.68,Ki=2.11nM
External links
PDB RCSB:2nw4, PDBe:2nw4, PDBj:2nw4
PDBsum2nw4
PubMed17008401
UniProtP15207|ANDR_RAT Androgen receptor (Gene Name=Ar)

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