Structure of PDB 2ntc Chain A

Receptor sequence
>2ntcA (length=127) [Search protein sequence]
VEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSV
TFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYL
MYSALTRDPFSVIEESLPGGLKEHDFN
3D structure
PDB2ntc The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A N153 T155 R202 H203 R204 A207 N22 T24 R71 H72 R73 A76 PDBbind-CN: Kd=60nM
BS02 dna A S147 H148 A149 F151 S152 N153 R154 N227 S16 H17 A18 F20 S21 N22 R23 N96 PDBbind-CN: Kd=60nM
Gene Ontology
Molecular Function
GO:0003688 DNA replication origin binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2ntc, PDBe:2ntc, PDBj:2ntc
PDBsum2ntc
PubMed17253903
UniProtQ98ZP7

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