Structure of PDB 2nsj Chain A

Receptor sequence
>2nsjA (length=162) Species: 562 (Escherichia coli) [Search protein sequence]
PARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAQRTPDKLFSFAE
SAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYS
IVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQT
DEVLENPDPRGA
3D structure
PDB2nsj N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
ChainA
Resolution2.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.99.18: 5-(carboxyamino)imidazole ribonucleotide mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2R A G15 S16 S18 D19 S43 A44 Q45 R46 A70 G71 A74 H75 L76 G9 S10 S12 D13 S37 A38 Q39 R40 A64 G65 A68 H69 L70 MOAD: Kd=16.3uM
PDBbind-CN: -logKd/Ki=4.79,Kd=16.3uM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity
GO:0042802 identical protein binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2nsj, PDBe:2nsj, PDBj:2nsj
PDBsum2nsj
PubMed17298082
UniProtP0AG18|PURE_ECOLI N5-carboxyaminoimidazole ribonucleotide mutase (Gene Name=purE)

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