Structure of PDB 2nsh Chain A

Receptor sequence
>2nshA (length=163) Species: 562 (Escherichia coli) [Search protein sequence]
PARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAQRTPDKLFSFAE
SAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYS
IVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQT
DEVLENPDPRGAA
3D structure
PDB2nsh N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.99.18: 5-(carboxyamino)imidazole ribonucleotide mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NIA A G15 S16 D19 S43 A44 Q45 R46 A70 G71 H75 G9 S10 D13 S37 A38 Q39 R40 A64 G65 H69
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity
GO:0042802 identical protein binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2nsh, PDBe:2nsh, PDBj:2nsh
PDBsum2nsh
PubMed17298082
UniProtP0AG18|PURE_ECOLI N5-carboxyaminoimidazole ribonucleotide mutase (Gene Name=purE)

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