Structure of PDB 2nom Chain A

Receptor sequence
>2nomA (length=325) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
PSPAVVGRSLVNSFKQFHTRHVDATYRLVLDCVAAVDPLMRLYTFGSTVV
YGVHEKGSDVDFVVLNKTDVEDGKGGDAATQVAKGLQADILAKLARVIRQ
KHLSWNVEEVRRTRVPVVRVKGGGAVDFDITAYRRNGVRNSALLRAYFEQ
NPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQF
VPPSTIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQ
VISLNRPGITTKEELDWTKSAEDFARMNGEKVHYQWCIEDPYELNLNVGR
NVTPLKRDFLRRHLEKARDTALLTI
3D structure
PDB2nom UTP-bound and Apo Structures of a Minimal RNA Uridylyltransferase.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D66 D68 D59 D61
BS02 MG A D66 D68 D136 D59 D61 D129
BS03 DUT A F52 G53 S54 S65 G144 N147 S148 K169 K173 S188 Y189 F45 G46 S47 S58 G137 N140 S141 K162 K166 S181 Y182
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0071076 RNA 3' uridylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0020023 kinetoplast

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2nom, PDBe:2nom, PDBj:2nom
PDBsum2nom
PubMed17189640
UniProtQ381M1|TUT4_TRYB2 Terminal uridylyltransferase 4 (Gene Name=TUT4)

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