Structure of PDB 2nnu Chain A

Receptor sequence
>2nnuA (length=201) Species: 333760 (Human papillomavirus 16) [Search protein sequence]
SMETLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREM
GFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSL
EVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVE
GQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSV
F
3D structure
PDB2nnu Structure of the Papillomavirus DNA-Tethering Complex E2:Brd4 and a Peptide that Ablates HPV Chromosomal Association.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S0 R7 R37 Y44 K66 A69 L70 I73 S1 R8 R38 Y45 K67 A70 L71 I74
Gene Ontology
Biological Process
GO:0006275 regulation of DNA replication
GO:0006355 regulation of DNA-templated transcription
GO:0016032 viral process

View graph for
Biological Process
External links
PDB RCSB:2nnu, PDBe:2nnu, PDBj:2nnu
PDBsum2nnu
PubMed17189190
UniProtP03120|VE2_HPV16 Regulatory protein E2 (Gene Name=E2)

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