Structure of PDB 2nna Chain A

Receptor sequence
>2nnaA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
DIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLF
RRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVT
LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKI
SYLTFLPSADEIYDCKVEHWGLDEPLLKHWEP
3D structure
PDB2nna A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 Y22 R52 R53 F54 N62 V65 H68 N69 I72 R76 Y10 Y24 R54 R55 F56 N64 V67 H70 N71 I74 R78
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2nna, PDBe:2nna, PDBj:2nna
PDBsum2nna
PubMed17629515
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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